The HIV Host Interactions Team

Marianne Jansson

PhD, Professor

Read about Marianne in the Research Portal

Marianne´s publications

"My research is focused on understanding HIV host interactions and the impact these have on disease progression, by deciphering mechanisms behind protective and pathogenic immune responses in HIV-1 and HIV-2 infections. The goal is to contribute to optimized treatment and provide clues to how an effective HIV vaccine or cure should be designed."

 Sara Karlson

  Senior Laboratory Assistant

  MSc. Biomedicine

  Read about Sara in the Research Portal

  Sara's publications

" HIV research has always been very intriguing to me and this contributes to my long-term interest in the field. Working as a lab technician for three different groups gives me the opportunity to work with several projects with different aims and approaches. This equips me with a wide array of techniques and skills. I also have the privilege to train students with different academic backgrounds."

 Malin Neptin

 Biomedical Scientist

 BSc. Biomedical Laboratory Science

 Read about Malin in the Research Portal

 Malin's publications

" I joined the group in January 2020 after more than 20 years of work in two other groups at Lund University (9 years of work with MS and Rheumatoid arthritis and 12 years with Diabetes type 2) and now it´s time to change to a new field. I´m looking forward to learning a lot of new techniques and get knowledge about HIV-research."

Zsófia Szojka

PhD, Associate Researcher

Read about Zsófia Szojka in the Research Portal

Zsófia´s publications

"HIV-2 research has always been my main interest. I was previously focused on HIV-1 and HIV-2 dual infection, HIV-2 mono-infection and in vitro characteruization of HIV-2 Protease.

My new goal is to characterize HIV-2 elite controllers, a unique group of HIV-2 infected individuals. This research will provide better understanding of HIV-2 infection, and will show a promising potential in the fight against HIV."

Eva-Maria Fenyö

MD, PhD, Professor Emerita

Read about Eva-Maria in the Research Portal

Angelica Palm

PhD, Associate Researcher

Ph.D in Clinical Virology

Read about Angelica in the Research Portal

Angelica´s publications

My research is focused on studying the mechanisms underlying differences in HIV disease progression. During my Ph.D. I investigated the influence of viral genetics on HIV-1 and HIV-2 disease progression and since 2020, my research is instead focused on the immunological aspects of HIV infection. More specifically, I’m investigating how the immune response is shaped by HIV-1 and HIV-2 and how this translates to differences in disease progression.  

Projects:

- Resolving the immune cell landscape in HIV-1 and HIV-2 infection using single-cell RNA sequencing

- Characterizing the virus-specific T cell population in HIV-1 and HIV-2 infected individuals.

- Investigating the innate immune response to HIV-1 and HIV-2 in vitro.

Emil Johansson

  PhD, Postdoctoral Fellow

  MSc. Biomedicine

  Read about Emil in the Research Portal

  Emil's publications

" The overarching goal of my Ph.D. is to study the mechanisms underlying the difference in HIV-1 and HIV-2 pathogenicity. By creating chimeric HIV viruses we will be able to dissect the influence of viral genetic factors on viral pathogenicity. Ex vivo infections of human tonsil tissue explants with chimeric viruses will likely provide valuable insight into key virus-host interactions that distinguish HIV-1 and HIV-2 infections.."

Projects

• Development of HIV-1 and HIV-2 gene-specific chimeric viruses
• Analysis of infectivity and replicative capacity of HIV-1 and HIV-2 isolates and chimeric viruses in lymphoid cells and tissue
• Identification of mechanisms behind HIV-2 interference with HIV-1 replication in dual infections of lymphoid cells and tissue

• Characterization of HIV-2 cell tropism and reservoirs, compared to HIV-1, in lymphoid tissue 

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